My plan is to make short interviews using the same 6 questions with today’s life extension supporters/bloggers around the blogosphere. The first answerer will be Reason, the engine behind Fight Aging! and Longevity Meme.
Here are the questions:
1. What is the story of your life extension commitment?
2. Is it a commitment for moderate or maximum life extension?
3. What is your favourite argument supporting human life extension?
4. What is the most probable technological draft of human life extension, which technology or discipline has the biggest chance to reach it earliest? (regenerative medicine, nanotechnology, gene therapy, caloric restriction, bionics, hormones, antioxidants, …)
5. When?
6. What can blogs do for LE?
Deep, healthy lifespan extension 
1. What is the story of your life extension commitment?
I have adopted life extension as a hobby. I now study microbiology, proteomics and molecular design about 20 hours per week and plan to guide the next 20-40 years of my career through bioinformatics and eventually into de novo drug design with an emphasis on aging solutions.
2. Is it a commitment for moderate or maximum life extension?
maximum.
3. What is your favourite argument supporting human life extension?
1. Future generations will certainly have it. Why not ours?
2. Eliminating the suffering that accomapanies aging will make humanity more humane.
4. What is the most probable technological draft of human life extension, which technology or discipline has the biggest chance to reach it earliest? (regenerative medicine, nanotechnology, gene therapy, caloric restriction, bionics, hormones, antioxidants, …)
I think all of the present “big potentials” like stem cells, gene therapy, etc will contribute to modest extensions to average and maximum life expectancy but I believe that the most significant gains will fall out of accurate and large scale computer models that can simulate the emergent properties of protein-protein and protein-enzyme interactions. These will be the tools of the multi-disciplined systems biologists of the future. I see advancements in life extension tightly bound in a triple helix with proteomic knowledge and computing power.
5. When?
In 20-40 years we will see the most dramatic returns IMO.
6. What can blogs do for LE?
resonance.
Jim, thx for the answers, it’s fascinating, I’ll put them on the blog as an independent post next week, if you agree. For big-scale human body models we need big-scale non-invasive measure tools, which continuously scan the human body hunting for physiological information, forming the input of the models.
Feel free to post. I agree that we’ll need some new tools. The advancements we’re seeing in fourescence and imaging combined with high-throughput automation give me hope that such tools are on the horizon if their prototypes aren’t already evolving in labs today. The same tools we’re using for fighting cancer, e.g. those that are screening for biomarkers etc., will also be useful for fighting aging.
plusone science model quesions