Thesis live: 1.1 Turnover or Every cell has a lifespan

In the live thesis building blogxperiment I edit (digest, compile, write, rewrite, delete) my ongoing doctoral thesis in blog posts and put the parts together on thesis live. The title: The physiologic role of stem cells in tissues with different regenerative potential. 1.1 Stem cells and regenerative medicine: basic concepts /turnover: cellular turnover/ The concept… Continue reading Thesis live: 1.1 Turnover or Every cell has a lifespan

The domesticated biotech future according to Freeman Dyson

Freeman Dyson, old school physics hero conceptualized his rather philosophical thoughts on future biotechnology in a visionary essay in The New York Review of Books, Volume 54, Number 12 · July 19, 2007. What is surprising to me that according to Dyson “our biotech future” is centered around genetic engineering only, and there is not… Continue reading The domesticated biotech future according to Freeman Dyson

Are we really in the age of Regenerative Medicine 2.0? A comparison by Chris Mason

In the age of compelling technology analogies and nomenclatures it was unavoidable that somebody at last identifies enough differences in the history of industrial regenerative medicine to tell Regenerative Medicine 1.0 from 2.0. The man behind is Chris Mason, Group Leader of Stem Cell + Regenerative Medicine Bioprocessing Unit, University College London and cofounder and… Continue reading Are we really in the age of Regenerative Medicine 2.0? A comparison by Chris Mason

An argument supporting systemic regenerative medicine as a life extension tool

The incentive of this argument is a comment on a post over at fellow life extension blog Fight Aging! titled You Can’t Row the Whole Distance With Oars Made of Stem Cells. 1. Currently the biggest grants in life sciences are in regenerative medicine and stem cell biology. 2. The rate of progress is very… Continue reading An argument supporting systemic regenerative medicine as a life extension tool

The birth of the stem cell niche concept: Schofield, 1978

In David Scadden‘s elegant review on The stem-cell niche as an entity of action I found the historically first article in which the concept of the stem cell niche was proposed: “The concept of a niche as a specialized microenvironment housing stem cells was first proposed by Schofield almost 30 years ago in reference to… Continue reading The birth of the stem cell niche concept: Schofield, 1978