I found this picture of Aubrey de Grey with his book Ending Aging on his head at the BIL conference in Quinn Norton‘s Flickr Stream. Quinn Norton is a bodyhacker technophiliac journalist photographer. Robust, healthy lifespan extension can easily be interpreted as an extreme body-, life- and biohack so no wonder that more and more… Continue reading Life extension people are happy: keep living, please!
Looks like the scientist coalition behind healthy life extension is widening. In line with that the question Why was life extension ruled out of the 14 Grand Engineering Challenges? is fading away. Here is an Aubrey de Grey message from my mailbox: All details, including forms for abstract submission and online registration, are at the… Continue reading Understanding Aging Conference in L.A.: de Grey, Conboy, Wagers and many others…
In order to slow the progress of aging and prevent age-related disease (which is not the same as figuring out a robust engineering plan for unlimited healthy life extension) biological measures (biomarkers) of aging or disease mechanisms are needed that anticipate clinical disease and are sensitive to functional organism aging. The American Federation for Aging… Continue reading Biomarkers of aging conference in New York City
Quick storytelling through citations (alert from Jim Hardy, thanks): Cell: Nutrient-Sensitive Mitochondrial NAD+ Levels Dictate Cell Survival A major cause of cell death caused by genotoxic stress is thought to be due to the depletion of NAD+ from the nucleus and the cytoplasm. Here we show that NAD+ levels in mitochondria remain at physiological levels… Continue reading “Mitochondrial Oasis Effect”: fasting => NAD+ up in mitos => cell survival
Linda Powers is the managing director and co-founder of Toucan Capital Corp, a $120 million venture capital fund (SBIC) focused on seed and early-stage life science and advanced technology investments (the fund markets itself as the The Leading US Investor in Stem Cells and Regenerative Medicine). Out of here insights and facts presented on the… Continue reading SENS3: The stem cell marketplace by Linda Powers, Tucan Capital (slides)
Embedded on the slideshow below 9 slides of Michael Rose‘s presentation called Slowing and then stopping aging on the SENS3 conference on the 9th of September. (Photos made by me with the iPhone.) Rose’s argument was: Aubrey de Grey’s original SENS proposal is based on the non-evolutionary assumption that aging is a process of accumulating… Continue reading Michael Rose, evolutionary SENS and aging as a loss of adaptation (slides)
James Clement, attorney and serial entrepreneur is the new Executive Director of the World Transhumanist Association (“WTA“). Press Release Read our November, 2006 blogterview with James Clement on his life extension commitment: Maximum Life’s James Clement: what can a lawyer do for life extension? From the blogterview: 3. What is your favourite argument supporting human… Continue reading James Clement, Pimm’s former blogterviewee is WTA’s new Executive Director
Unfortunately replicative senescence in dividing somatic cell populations through telomere shortening and organismal level aging is not as strictly related as the September Wired (not online yet) issue’s Artifacts From the Future section suggests:
The Buck Institute in Novato, California is a rich private research center focusing on aging with the mission of “extending the healthy years of life”. They have a real interdisciplinary staff, exactly the one that is needed for studying aging, which is a notoriously multifactorial, multicausal, atypical and complex biological phenomenon. One of the faculty… Continue reading Ask a good scientist in a San Francisco Cafe: The Reality of Age Research
As you might know Technorati, the premiere blog search engine was redesigned about a week ago, and now it is intended to be a more universal search engine which is mirrored in the current subtitle on the page: “Zillions of photos, videos, blogs and more.” Here is what you can find after typing the term… Continue reading Everything Technorati knows about life extension
You can now pre-order Ending Aging: The Rejuvenation Biotechnologies That Could Reverse Human Aging in Our Lifetime at Amazon written by Aubrey de Grey and Michael Rae which is the most detailed, although popular exposition of the SENS (Strategies for Engineered Negligible Senescence) plan to defeat aging. Aubrey was kind enough to mail me the… Continue reading Content of Ending Aging, Aubrey de Grey’s coming life extension book
There is a formulation of the argument on why aging should be considered as an unnatural process by Atul Gawande in the current The Way We Age Now report in The New Yorker: “..scientists do not believe that our life spans are actually programmed into us. After all, for most of our hundred-thousand-year existence—all but… Continue reading Why aging is an unnatural process? An argument from Atul Gawande
In recent culture, technological life extension is considered to be a form of hacking, as 2Dolphins says a “hacker is someone who enjoys the intellectual challenge of creatively overcoming or circumventing limitations — someone who makes things work beyond perceived limits through unconventional means or skills.” In hacking there is also a DIY element too.… Continue reading Life extension: body hack and/or life hack?
Following Reason’s links at Fight Aging here is a little conference webcasting from the Edmonton Aging Symposium. You also can read a Conference Report at Ouroboros. There was a Symposium Live Streaming where for the very nominal fee of $5 CAD per connection to cover bandwidth costs people could watch the majority of presentations in… Continue reading 3 Edmonton Aging (Life Extension) Symposium videos
The Edmonton Aging Symposium starts today. Based on the program and speakers you can expect hot debates: Huber Warner, Aubrey de Grey, Irina Conboy, Amit Patel, Judith Campisi. I hope that the discussions will be hot, clarifying, perspective and scale conscious (quantitative enough), backed by strict scientific arguments. The organizing principle of the sessions seems… Continue reading Edmonton Aging (Life Extension Technologies) Symposium starts, March 30-31.
Upon a discussion with Anna 1 month ago, the question arised whether life extension might be interpreted as a green idea. She offered, that if people have the opportunity to extend their life significantly, paralell with this situation they find themselves in a more or less environmentalist position. Now back 2 steps: the question of… Continue reading Extension of life in green
Such a Californian story: Lorry I. Lokey, the founder of Business Wire will give a minimum of $33 million to help build a home for Stanford’s Institute for Stem Cell Biology and Regenerative Medicine. Lokey says: “The important thing to me is that stem cells might not only extend life, but also improve the quality… Continue reading 80 year old Lokey’s $33 million donation for Stanford Stem Cell Labs
The Coalition to Extend Life launched today an online petition to U.S. Congress and President in order to make the technological possibility of Indefinite Life Extension a national priority and public policy goal of the United States. They ask the power people to create the 4 main conditions that will make it possible. 1. a… Continue reading Unlimited Life Extension Petition to U.S. Congress and President: a good address?
The incentive of this argument is a comment on a post over at fellow life extension blog Fight Aging! titled You Can’t Row the Whole Distance With Oars Made of Stem Cells. 1. Currently the biggest grants in life sciences are in regenerative medicine and stem cell biology. 2. The rate of progress is very… Continue reading An argument supporting systemic regenerative medicine as a life extension tool
Check out Grailsearch.org, which was started at the end of January and is hosted by software engineer Jim Craig with a deep interest in aging and bioinformatics. Grailsearch is a “community web portal intended for use by biogerontologists, students of biogerontology, software engineers, biochemists or anyone else interested in working towards the search for systems… Continue reading Grailsearch.org: aging information from a systems biology perspective
Most of us believe that the massive spreading of an idea through the channels of society, say, ‘big-scale life extension technology is possible and worth realizing’, depends on highly influential people’s production and characteristics. So hardcore life extension supporters tend to think if Aubrey de Grey or Ray Kurzweil will hold another 120-120 presentations in… Continue reading Accidental influentials meet life extension: a breakthrough idea for 2007
Now we are after the Steve Jobs Keynote introducing the iPhone at Macworld Expo in San Francisco. I don’t know if the iPhone line will be the ultimate portable digital device everybody is dreaming about, but I do know, that when partial immortalization as a technology will be first introduced it will be by definition… Continue reading Steve Jobs style partial immortalization keynote: the iPimm
What can/will You do for life extension? Answer these questions first. Interviews in a temporal order: Reason, Chris Patil, Jim Craig, Aubrey de Grey, John Cumbers, Kevin Dewalt, Nick Bostrom, James Clement, David Kekich, Huber Warner, Mark Hamalainen, John Schloendorn. For me it is important to introduce here people with different professional background who are… Continue reading Life extension blogterviews in 2006
Forget about governmental funds for a minute. According to you which companies have the chance to develop an indefinite life extension technology? Let us assume that even today there exists a company, or a predecessor of it which can eventually realize indefinite LE and customize it. Will it be a biotech company, like Genentech, Geron,… Continue reading The first private company behind indefinite life extension: ?
Al Gore’s Inconvenient Truth, a movie-long effective presentation on climate change and crisis has made him the chief environmental evangelist of U.S. Incorporation. (I liked that he is doing his Keynotes himself, my Apps.) Now I have a better offer for Al Gore: be the first networking-presentation man of healthy life extension and an official… Continue reading Hey Al Gore: switch to life extension, aging is a more inconvenient truth
And the winner is…. Maximum life extension is deeply in your mind, people, on the search level and on the intention level too. The old school term, anti-aging also got 5,470,000 results. And the term ‘longevity’ is the most popular on the market: 16,800,000 results. With GoogleFight. Just do it.
John Schloendorn has a master’s degree in biochemistry at the University of Tuebingen, Germany. Currently he is a graduate student at Arizona State University’s Biodesign Institute, USA. John is heavily involved in the LysoSENS project of the Methuselah Foundation, which aims to remove some intracellular waste products for example via microbe-derived hydrolases targeted to the… Continue reading John Schloendorn, the LysoSENS connection: chat on life extension
Mark Hamalainen is a young PhD student at Cambridge University at the mitochondrion lab of Ian Holt. Mark received a Bachelor of Science Honours degree in biochemistry and computing from Queen’s University in Kingston, Ontario. He also had research training as a visiting scholar at the California Institute of Technology and the Biodesign Institute at… Continue reading Mark Hamalainen, the MitoSENS fellow: blogterview on life extension
Huber R. Warner is a biochemist by profession and he initiated and participated in the development of many research areas including: cellular senescence, oxidative stress, apoptosis, functional genomics, the intervention testing program, and premature aging models. He currently serves on the editorial board of Mechanisms of Ageing and Development, is the editor of the Journal… Continue reading Moderate life extension: yes, maximum: no, interview with Huber Warner
Critical thinking is crucial to every successful scientific and technological project. In order to consider any attempt to the extension of life in details,we have to take a look at the other side of the coin. So in the future I try to blogterview some experts, scholars, philosophers, activists, …who are opposing some concrete points… Continue reading Questions to contra life extensionists: rational pitfalls
David A Kekich is a heavyweight venture capitalist and investment expert. In 1999, he founded the Maximum Life Foundation, a corporation dedicated to curing aging related diseases. His LIVES™ financial strategy will finance the research needed to profitably develop life extending technologies. Kekich, who is also a lifestyle life extensionist, and very aware of current… Continue reading Maximum Life CEO David Kekich: the investment strategy of life extension
James Clement is an attorney and serial entrepreneur. He is the Chief Operating Officer of Maximum Life Foundation which supports aging and life extension research with a mature and secure VC fund strategy (next blogterviewee, David Kekich, C.E.O. of MaxLife). 1. What is the story of your life extension commitment? I have been interested in… Continue reading Maximum Life’s James Clement: what can a lawyer do for life extension?
Nick Bostrom is an analytic philosopher by profession in Oxford, but he has a strong background in science too. He is also the co-founder and current chair of the World Transhumanist Association. 1. What is the story of your life extension commitment? I did not think much about the topic until I learned about various… Continue reading Life extension interviews: Nick Bostrom and the philosopher’s point of view
Kevin Dewalt is an American technology professional, presently working at a VC. Kevin is a strong life extension supporter. We’ve met online at Baris Karadogan’s blog. I specially liked his “happy argument” for maximum life extension on the psychological level, see answer 3. 1. What is the story of your life extension commitment? When I… Continue reading Kevin Dewalt’s answers: technology professional, lifestyle life extensionist
Dear Reader, if You are stem cell researcher, life scientist, medical doctor, scholar, activist, bloggers, IT professional, venture capitalist, philosopher, economist, politician, decision maker, businessman, biotech- or big pharma manager, plastic surgeon, hairdresser… who support life extension, please answer the questions below and send me to [attilacsordas][at][gmail.com] to get blogterviewed.
John Cumbers made the Drosophila CHiP protocol video. He is a graduate student at the Tatar lab in Brown University, USA. Below are his answers to the blogterview questions and through answer 5 you can take a fresh look at the bottom-up approach of synthetic biology.
The spectrum of the life extension blogterviewees is broad: scholars, activists, IT people, VC folks, … and is broadening further. Here are 2 more activists/bloggers who put their answers to their blog: Anne Corwin and the aphoristically dense Phil Bowermaster. Thanks for answering. I ‘d like to emphasize that I modified questions 4-5, and introduced… Continue reading 2 more bloggers’ answers: Anne Corwin and Phil Bowermaster
Aubrey de Grey is the man, who first made serious, scientifically conceptualized life extension speech acceptable within scholarly circles through good timing, well-done strategy and with a little bit of luck. The rest is … (I’ve slightly modified the original question 4 and separated questions concerning the probable technologies of moderate and maximum life extension.)… Continue reading Blogterview with Aubrey de Grey: life extension stories
There was a very interesting comment dialogue last week apropos of Aubrey de Grey‘s TED talk, and the host was Baris Karadokan’s blog called From Istanbul to Sand Hill Road subtitled High-tech, venture capital, creativity and innovation. Here are some details. Link storytelling idea source
Briefly: A lot. As you might have noticed, for me as biotechnologist/life extensionist, the most important reference group is the group of IT people, because of the engineering approach, software-hardware tools, intuition concerning technology and funds. After Reason and Chris, our next answerer is Jim Craig, who published his answers here as a comment first… Continue reading The bioinformatics bet: what can IT folks do for life extension?