1. DNA methylation age of human tissues and cell types by Steve Horvath: This is the type of relevant data mining study most bioinformaticians are dreaming of: you pull together a large body of publicly available datasets (CpG methylation) that are not too heterogeneous (Infinium type II assay on Illumina 27K or Illumina 450K array platform), derive robust… Continue reading Three links in Aging, Regenerative Medicine & Healthy Lifespan Extension: 17 December 2013
1. Is aging linear or does it follow a step function? A good & simple question on Quora that surprised even Aubrey de Grey. If you are a bioinformatician out there – looking for a new pet project – go pull together some data & try to plot it! Let me know if you have something.… Continue reading Three links in Aging, Regenerative Medicine & Healthy Lifespan Extension: 8 December 2013
Here’s an edited version of my Quora answer to the question: “Life Decisions: How do people who are talented in many areas decide what to do with their lives?“ Let me provide a personal story illuminating one option Ruchira is talking about: “pick a complex challenge that you are passionate about, that will require many different… Continue reading How to build a colorful life around life extension using different skills: a personal story
How do you interpret the following situation: we have a life extension technologist whose all endeavors is about pushing this issue to its very limits and making things possible but on the other hand this very life extensionist himself is not driven by actually living as long as he can. It seems that SENS theorist… Continue reading Are life extensionists mainly driven by a desire to actually live a long time?
assuming we are heading into a global economic crisis…
I had problems with my handwriting since elementary schools, or at least my teachers had continuous problems with it. Even during my university years I was asked sometimes to read out loud my essays, papers to them otherwise risking bad grades. Maybe it’s because I am a hidden right-handed using my left hand for writing… Continue reading Even ugly handwriting can fit the informal nature of SciFoo
It was already known that amongst the Google top people Sergey Brin is the one who is most interested in pushing biotechnology and the biomedical sciences: in his Stanford years he was interested in biology courses according to The Google Story, he married Anne Wojcicki (who graduted from biology at Yale), Google invested $4.4 million… Continue reading Sergey Brin, Gly2019Ser & a real chance against Parkinson disease/aging!
If “Science has a really serious marketing problem” as Larry Page observed, then life extension technologies face even bigger marketing problems. I am definitely not a marketing expert but realized the problem early on when thinking about the lag-phase period of a robust life extension technology. So I made a short email interview with Dave… Continue reading The marketing problem of life extension technologies
Last year I was probably the only SciFoo Camper with an explicit life extension commitment. I suggested & held a session which was related a bit to partial immortalization but was rather about the systems biology perspective in general, illustrated with some examples. So throughout the terrific SciFoo Camp 2007 life extension as a conversation… Continue reading Life extension people & session at SciFoo 2008, Googleplex!
Finally Chris over at Ouroboros came up with the idea and the quick implementation of Hourglass, a blog carnival devoted to the biology of aging/biogerontology. For some reason I am not an explicit supporter of blog carnivals – many of my posts were chosen by carnival editors but I never hosted one -, but Hourglass… Continue reading Hourglass, a blog carnival devoted to the biology of aging
This is how my Macbook saw Aubrey de Grey’s talk exactly 1 week ago on the AGING preconference at UCLA.
The “Understanding Aging: Biomedical and Bioengineering Approaches” conference will be held from June 27-29, 2008 at UCLA organized by Aubrey de Grey, Irina Conboy and Amy Wagers. I like to call it UndertsEnding Aging in myself and I am excited to go to LA and meet new people also people from SENS3. Yesterday I created… Continue reading Understanding Aging Conference on FriendFeed!
Just landed in my mailbox, emphasis added by me: Dear Attila, I would like to provide you with a copy of the press release to be distributed via press release distribution sites on Wednesday. We will also put it on our site within a few hours after this email so you can confirm its authenticity.… Continue reading The Biogerontology Research Foundation receives charitable status, UK
90 is the New 50: The Science of Longevity via Brandon Keim, Wired Science: Sunday, June 1, 7:00 PM – 8:30 PM,NYU – Kimmel Center for University Life Will it one day be possible to take a pill to stay young? How will an average life expectancy of beyond a hundred years affect society and… Continue reading The Science of Longevity at The World Science Festival, June 1, NYC
I asked the following question on Twitter recently: “A question for all of you Twitterers: Are you for, against, or just neutral on healthy life extension? How long would you like to live? Why?” I have to tell you it’s hard to give good links to the whole chat without noise. Maybe on FriendFeed. To… Continue reading Short Twitter/FriendFeed chat on life extension
Following the little Google trend watch on life extension, here is an interesting comparison complemented with a Google Fight: and the fight:
When Google Trends went live one of my first search was for “life extension” and posted a little analysis about that. Here is a quick update with a serious question about the stagnating or declining popularity of ‘life extension’ searches. Explanations are needed. /I don’t know the exact search scale for the y axis/.
In No kidding, I am a cum laude philosopher, and so can you! it turned out that finally I got a philosophy diploma. That said, from now on I am officially qualified to think on the big questions of life. For instance, I can find out new arguments and concepts and I can answer (or… Continue reading “What is the meaning of life?” for a life extensionist
Michael Kingsley – diagnosed with Parkinson disease at the age 42 – wrote an utterly fatalist, sad&straight and death conscious essay entitled Mine Is Longer than Yours on the last boomer game he calls competitive longevity published in the New Yorker. This piece is the dark counterpart of the recent Wired Kurzweil coverage on Mr.… Continue reading Michael Kingsley on competitive, bitter, boomer longevity
Today’s meditation is for serious healthy life extension supporters to consider the following 36 – general and sometimes corporate – idea killers concerning our little project: 1. We tried that already 2. We’ve never done anything like that before. 3. Has anyone ever done anything like that before? 4. That never works 5. You’re fired… Continue reading 36 Life extension idea killers: mental practice for the pros!
I’ve always loved the following scene from LOTR, but I’ve always imagined that they are the words of a man who is in a healthy physiological condition due to a robust life extension technology and not due to a mystical ring: Bilbo: “Today is my one hundred and eleventh birthday!” Hobbits: “Happy birthday!” Bilbo: “Alas,… Continue reading Larry Page is 35 years old today: long live to live long enough!
Last year I approached a powerful Wired editor with the following story pitch: “A full and deep but cool report on the current (scientific) life extension technologies, persons, battles, camps, grants, problems, perspectives.” His reply was a diplomatic and definite naysaying: “Thanks for the idea. Alas, we’ve done *way* too many stories on life-extension over… Continue reading Kurzweil follow-up in life extension exhausted Wired
I found this picture of Aubrey de Grey with his book Ending Aging on his head at the BIL conference in Quinn Norton‘s Flickr Stream. Quinn Norton is a bodyhacker technophiliac journalist photographer. Robust, healthy lifespan extension can easily be interpreted as an extreme body-, life- and biohack so no wonder that more and more… Continue reading Life extension people are happy: keep living, please!
“The best way to predict the future is to invent it.” – said Alan Kay, computer legend in 1971. Recently I had a comment dialogue with Chris on whether state-supported research or industrial business enterprises can (or should) lead to big progress in robust and healthy life extension technologies. Besides the government and corporation coin… Continue reading Biotech DIY for aging/life extension research: the double future?
Scott Wainner – an old timer, professional internet revenue generator and recent maximum healthy life extension advocate (the ideal target group) – wants you (in this case, me) to blog about life extension for $20 (first 100 bloggers only) and thereby also boosts his site’s traffic (I am sure there is a special marketing term… Continue reading The $20 life extension blogging challenge and change
Huffington Post, Fortune’s Stanley Bing: The Next Big Thing? Please pay extra attention to the language here (especially transmogrification). Human genome schmutz: Nobody wants to get old or worse, appear old. And forget about dying. That’s the ultimate bummer. Genetic research has been held back recently by a series of disasters too terrible to mention… Continue reading Very well informed Stanley Bing on life extension
Looks like the scientist coalition behind healthy life extension is widening. In line with that the question Why was life extension ruled out of the 14 Grand Engineering Challenges? is fading away. Here is an Aubrey de Grey message from my mailbox: All details, including forms for abstract submission and online registration, are at the… Continue reading Understanding Aging Conference in L.A.: de Grey, Conboy, Wagers and many others…
I emailed some of my life extension supporter friends because I think we have a ‘future’ situation: Healthy life extension is not 1 out of the 14 Grand Engineering Challenges…that can be realistically met, most of them early in this century according to the Committee on Grand Challenges for Engineering with members such as Larry… Continue reading Why was life extension ruled out of the 14 Grand Engineering Challenges?
…that can be realistically met, most of them early in this century according to the Committee on Grand Challenges for Engineering with members such as Larry Page, Dean Kamen, Craig Venter, Robert Langer and …lifestyle life extensionist, nanovisionary Ray Kurzweil. There is a challenge though called Engineer better medicines and the essay behind looks as… Continue reading Healthy life extension is not 1 out of the 14 Grand Engineering Challenges…
Thanks to Kevin, you can now watch the video too: Colbert: “But if people lived to be a 1000 years old won’t that kill any ability for humans to take risks cause if I’ve known I lived to be a 1000 I am not going to cross the street because you can’t cure being hit… Continue reading Aubrey de Grey on Colbert Report (video) and the housing market in heaven
I just got the alert from Kevin Dewalt: “Aubrey is scheduled to be on Colbert tonight in case anyone is watching.” Remember the recent case when Good Morning America cancelled the scheduled airtime for Aubrey de Grey saying the whole life extension subject was “too sciencey“. Update: Aubrey de Grey on Colbert Report (video) and… Continue reading Aubrey de Grey on the Colbert report tonight?
One strategy (call it Life Extension Gets Personal) to raise awareness for the idea and technology of healthy life extension is to publicly encourage life extension “coming outs” on behalf of mainstream celebrities. In order to get an academic legitimacy for LE (which is one of the most important aim of Pimm) I am interested… Continue reading Craig Venter and the life extension drive: blogterview questions
The Economist print edition (Jan 3rd) has a summary article on the current healthy and scientific life extension scene starting with Aubrey De Grey’s engineering, umbrella SENS approach and talking about anti-oxidants, mitochondria, sirtuin activators and stem cell based regenerative medicine amongst others. To my positive surprise the unknown writer of the article (do you… Continue reading Partial immortalisation goes mainstream with an ‘s’ – thanks to the Economist!
Philip Campbell, the open editor-in-chief of Nature was asked by John Brockman under the cover of the 2008 Edge Annual Question: WHAT HAVE YOU CHANGED YOUR MIND ABOUT? WHY? Campbell writes in his thoughtful answer: “I’ve changed my mind about the use of enhancement drugs by healthy people. A year ago, if asked, I’d have… Continue reading Nature Editor-in-Chief’s changed mind on enhancement drugs for healthy people
In the 15 November Nature issue Judy Illes neurology professor turned neuroethics expert reviews Enhancing Evolution: The Ethical Case for Making Better People by John Harris and Ending Aging: The Rejuvenation Breakthroughs That Could Reverse Human Aging in Our Lifetime by Aubrey de Grey & Michael Rae. From the review: “Ending Aging is a more… Continue reading The received view in 3.5 paragraphs on Ending Aging in Nature (part 1)
After all, what customers can really expect of personal genome services that companies like 23andMe can offer beyond knowing whether they have a perfect pitch or not? If the service can really help in minimizing the risk of life threatening diseases, than the real expectation is to live longer by using those personalized/commercialized genome data.… Continue reading The life extension bonus effect of personal genome services: +10 years?
Let’s meet the informal version of the ‘pro-aging trance’ in a portrait on Aubrey de Grey in the Washington Post (thanks for the tip, Jim): Why is it, when you bring up the idea of living forever — even if robust and healthy, not drooling on your shoes — some people just recoil viscerally? “It’s… Continue reading Robust life extension reaches the Washington Post on Halloween day
Robert Lanza is now the Chief Scientific Officer of Advanced Cell Technology, while Michael West is voluntarily stepping down as the company’s President and Chief Scientific Officer and jumps into the CEO seat of BioTime Inc.. Lanza and West are 2 legendary figures in the biotech industry, and here are 2 interesting things concerning them:… Continue reading Lanza up, West down at Advanced Cell Technology
Recently I wrote a meeting report on the SENS3 conference for a very prestigious science journal, but finally it did not go through the filters. I knew that the chance for publication is small as the journal rarely publish such meeting reports and as it was in many respects an unconventional science conference. The standards… Continue reading Unpublished SENS3 conference report for mainstream scientists!
In order to slow the progress of aging and prevent age-related disease (which is not the same as figuring out a robust engineering plan for unlimited healthy life extension) biological measures (biomarkers) of aging or disease mechanisms are needed that anticipate clinical disease and are sensitive to functional organism aging. The American Federation for Aging… Continue reading Biomarkers of aging conference in New York City