1. DNA methylation age of human tissues and cell types by Steve Horvath: This is the type of relevant data mining study most bioinformaticians are dreaming of: you pull together a large body of publicly available datasets (CpG methylation) that are not too heterogeneous (Infinium type II assay on Illumina 27K or Illumina 450K array platform), derive robust… Continue reading Three links in Aging, Regenerative Medicine & Healthy Lifespan Extension: 17 December 2013
1. Is aging linear or does it follow a step function? A good & simple question on Quora that surprised even Aubrey de Grey. If you are a bioinformatician out there – looking for a new pet project – go pull together some data & try to plot it! Let me know if you have something.… Continue reading Three links in Aging, Regenerative Medicine & Healthy Lifespan Extension: 8 December 2013
Here’s an edited version of my Quora answer to the question: “Life Decisions: How do people who are talented in many areas decide what to do with their lives?“ Let me provide a personal story illuminating one option Ruchira is talking about: “pick a complex challenge that you are passionate about, that will require many different… Continue reading How to build a colorful life around life extension using different skills: a personal story
Kaiser Permanente alongside with UCSF plans for genetic analyses of an unprecedented 100,000 older Californians, the Technology Review writes in Massive Gene Database Planned in California The effort will make use of existing saliva samples taken from California patients, whose average age is 65. Their DNA will be analyzed for 700,000 genetic variations called single-nucleotide… Continue reading Aging-centric genetic health database in California: 100k people, ~65yrs, 700k SNPs, telomeres too
“for the discovery of how chromosomes are protected by telomeres and the enzyme telomerase” press release The award goes to Elizabeth H. Blackburn, Carol W. Greider and Jack W. Szostak. The problem of telomere/telomerases is highlighting the double but strictly related aging/cancer problem space: Blackburn Lab Greider Lab Szostak Lab
I had problems with my handwriting since elementary schools, or at least my teachers had continuous problems with it. Even during my university years I was asked sometimes to read out loud my essays, papers to them otherwise risking bad grades. Maybe it’s because I am a hidden right-handed using my left hand for writing… Continue reading Even ugly handwriting can fit the informal nature of SciFoo
Last year I was probably the only SciFoo Camper with an explicit life extension commitment. I suggested & held a session which was related a bit to partial immortalization but was rather about the systems biology perspective in general, illustrated with some examples. So throughout the terrific SciFoo Camp 2007 life extension as a conversation… Continue reading Life extension people & session at SciFoo 2008, Googleplex!