Problem: embryonic stem cell lines vary & iPS lines too

Finally I started to digest all the articles (usually on the streetcar on my way to work and home) from the recent Nature Insight: Regenerative Medicine and I try to pick up some stories for you (& interesting enough for me) from that, in case you are not lucky enough to have an available copy.… Continue reading Problem: embryonic stem cell lines vary & iPS lines too

Out of 8 embryo cells: if 1 turned to an ES cell, 7 could still become a child

At least I know how to start my stem cell comprehensive exam tomorrow (The trick is to use blastocyst medium supplemented with laminin and fibronectin): Human Embryonic Stem Cell Lines Generated without Embryo Destruction Young Chung, Irina Klimanskaya, Sandy Becker, Tong Li, Marc Maserati, Shi-Jiang Lu, Tamara Zdravkovic, Dusko Ilic, Olga Genbacev, Susan Fisher, Ana… Continue reading Out of 8 embryo cells: if 1 turned to an ES cell, 7 could still become a child

California embryonic stem cell dollars: beyond the embryonic phase

According to the newest Request For Applications (RFA) of the California Institute for Regenerative Medicine (CIRM), the New Cell Line Awards will support two categories of research: Category 1: Derivation of new hESC lines using excess or rejected early stage human embryos generated by in vitro fertilization. Category 2: Derivation of pluripotent human stem cell… Continue reading California embryonic stem cell dollars: beyond the embryonic phase

Unofficial and hypercritical peer review of a paper on p53’s role in hESC regulation

Once I wrote shortly about the following peer review paper which was popped out of my PubMed feeds to draw some attention to it: Han Qin, Tianxin Yu, Tingting Qing, Yanxia Liu, Yang Zhao, Jun Cai, Jian Li, Zhihua Song, Xiuxia Qu, Peng Zhou, Jiong Wu, Mingxiao Ding, Hongkui Deng Regulation of apoptosis and differentiation… Continue reading Unofficial and hypercritical peer review of a paper on p53’s role in hESC regulation

The first stem cell related Nobel prize: Martin Evans, 2007

The Nobel Assembly at Karolinska Institute has today decided to award The Nobel Prize in Physiology or Medicine for 2007 jointly to Mario R. Capecchi, Martin J. Evans and Oliver Smithies for their discoveries of “principles for introducing specific gene modifications in mice by the use of embryonic stem cells” Link It’s rather a 2/3… Continue reading The first stem cell related Nobel prize: Martin Evans, 2007

George Daley explains the source of Hwang’s “cloned” ES cells on Youtube

George Daley, the new president of the International Society for Stem Cell Research explains shortly the notorious case on a not embeddable (??????) YouTube video. If you are too busy to read the story, than watch it, it is 2 minutes and 13 seconds. Thanks for the video tip, Alexey Bersenev. If you have a… Continue reading George Daley explains the source of Hwang’s “cloned” ES cells on Youtube