After 20 something years of living a diverse educational and professional life motivated by healthy lifespan extension and dominated by science and technology I have reached the riskiest and most rewarding phase: launching a business around it and making it real. I have founded a startup, called AgeCurve Limited and we are already offering a product,… Continue reading AgeCurve Limited and Gen P: my business angle on aging and longevity
A snippet from the following interview: The Regeneration Generation: A Conversation With Bob Hariri, Vice-Chairman and Co-Founder of Human Longevity Inc.
If “Science has a really serious marketing problem” as Larry Page observed, then life extension technologies face even bigger marketing problems. I am definitely not a marketing expert but realized the problem early on when thinking about the lag-phase period of a robust life extension technology. So I made a short email interview with Dave… Continue reading The marketing problem of life extension technologies
Last year I was probably the only SciFoo Camper with an explicit life extension commitment. I suggested & held a session which was related a bit to partial immortalization but was rather about the systems biology perspective in general, illustrated with some examples. So throughout the terrific SciFoo Camp 2007 life extension as a conversation… Continue reading Life extension people & session at SciFoo 2008, Googleplex!
Finally Chris over at Ouroboros came up with the idea and the quick implementation of Hourglass, a blog carnival devoted to the biology of aging/biogerontology. For some reason I am not an explicit supporter of blog carnivals – many of my posts were chosen by carnival editors but I never hosted one -, but Hourglass… Continue reading Hourglass, a blog carnival devoted to the biology of aging
This is how my Macbook saw Aubrey de Grey’s talk exactly 1 week ago on the AGING preconference at UCLA.
The “Understanding Aging: Biomedical and Bioengineering Approaches” conference will be held from June 27-29, 2008 at UCLA organized by Aubrey de Grey, Irina Conboy and Amy Wagers. I like to call it UndertsEnding Aging in myself and I am excited to go to LA and meet new people also people from SENS3. Yesterday I created… Continue reading Understanding Aging Conference on FriendFeed!
Billionaire investor Carl Icahn (72) recently made the bloglines with his energetic position on the Microsoft – Yahoo deal. He has a blog too or at least it is coming soon since 01/31. /Having a blog for more than 3 months without any content is kinda equivalent with planning to sign up for Twitter but… Continue reading 80 is the new 50 so Carl Icahn has a blog without content.
Just landed in my mailbox, emphasis added by me: Dear Attila, I would like to provide you with a copy of the press release to be distributed via press release distribution sites on Wednesday. We will also put it on our site within a few hours after this email so you can confirm its authenticity.… Continue reading The Biogerontology Research Foundation receives charitable status, UK
90 is the New 50: The Science of Longevity via Brandon Keim, Wired Science: Sunday, June 1, 7:00 PM – 8:30 PM,NYU – Kimmel Center for University Life Will it one day be possible to take a pill to stay young? How will an average life expectancy of beyond a hundred years affect society and… Continue reading The Science of Longevity at The World Science Festival, June 1, NYC
I asked the following question on Twitter recently: “A question for all of you Twitterers: Are you for, against, or just neutral on healthy life extension? How long would you like to live? Why?” I have to tell you it’s hard to give good links to the whole chat without noise. Maybe on FriendFeed. To… Continue reading Short Twitter/FriendFeed chat on life extension
Michael Kingsley – diagnosed with Parkinson disease at the age 42 – wrote an utterly fatalist, sad&straight and death conscious essay entitled Mine Is Longer than Yours on the last boomer game he calls competitive longevity published in the New Yorker. This piece is the dark counterpart of the recent Wired Kurzweil coverage on Mr.… Continue reading Michael Kingsley on competitive, bitter, boomer longevity
Last year I approached a powerful Wired editor with the following story pitch: “A full and deep but cool report on the current (scientific) life extension technologies, persons, battles, camps, grants, problems, perspectives.” His reply was a diplomatic and definite naysaying: “Thanks for the idea. Alas, we’ve done *way* too many stories on life-extension over… Continue reading Kurzweil follow-up in life extension exhausted Wired
Scott Wainner – an old timer, professional internet revenue generator and recent maximum healthy life extension advocate (the ideal target group) – wants you (in this case, me) to blog about life extension for $20 (first 100 bloggers only) and thereby also boosts his site’s traffic (I am sure there is a special marketing term… Continue reading The $20 life extension blogging challenge and change
Huffington Post, Fortune’s Stanley Bing: The Next Big Thing? Please pay extra attention to the language here (especially transmogrification). Human genome schmutz: Nobody wants to get old or worse, appear old. And forget about dying. That’s the ultimate bummer. Genetic research has been held back recently by a series of disasters too terrible to mention… Continue reading Very well informed Stanley Bing on life extension
Looks like the scientist coalition behind healthy life extension is widening. In line with that the question Why was life extension ruled out of the 14 Grand Engineering Challenges? is fading away. Here is an Aubrey de Grey message from my mailbox: All details, including forms for abstract submission and online registration, are at the… Continue reading Understanding Aging Conference in L.A.: de Grey, Conboy, Wagers and many others…
I emailed some of my life extension supporter friends because I think we have a ‘future’ situation: Healthy life extension is not 1 out of the 14 Grand Engineering Challenges…that can be realistically met, most of them early in this century according to the Committee on Grand Challenges for Engineering with members such as Larry… Continue reading Why was life extension ruled out of the 14 Grand Engineering Challenges?
Thanks to Kevin, you can now watch the video too: Colbert: “But if people lived to be a 1000 years old won’t that kill any ability for humans to take risks cause if I’ve known I lived to be a 1000 I am not going to cross the street because you can’t cure being hit… Continue reading Aubrey de Grey on Colbert Report (video) and the housing market in heaven
I just got the alert from Kevin Dewalt: “Aubrey is scheduled to be on Colbert tonight in case anyone is watching.” Remember the recent case when Good Morning America cancelled the scheduled airtime for Aubrey de Grey saying the whole life extension subject was “too sciencey“. Update: Aubrey de Grey on Colbert Report (video) and… Continue reading Aubrey de Grey on the Colbert report tonight?
One strategy (call it Life Extension Gets Personal) to raise awareness for the idea and technology of healthy life extension is to publicly encourage life extension “coming outs” on behalf of mainstream celebrities. In order to get an academic legitimacy for LE (which is one of the most important aim of Pimm) I am interested… Continue reading Craig Venter and the life extension drive: blogterview questions
The Economist print edition (Jan 3rd) has a summary article on the current healthy and scientific life extension scene starting with Aubrey De Grey’s engineering, umbrella SENS approach and talking about anti-oxidants, mitochondria, sirtuin activators and stem cell based regenerative medicine amongst others. To my positive surprise the unknown writer of the article (do you… Continue reading Partial immortalisation goes mainstream with an ‘s’ – thanks to the Economist!
After all, what customers can really expect of personal genome services that companies like 23andMe can offer beyond knowing whether they have a perfect pitch or not? If the service can really help in minimizing the risk of life threatening diseases, than the real expectation is to live longer by using those personalized/commercialized genome data.… Continue reading The life extension bonus effect of personal genome services: +10 years?
In order to slow the progress of aging and prevent age-related disease (which is not the same as figuring out a robust engineering plan for unlimited healthy life extension) biological measures (biomarkers) of aging or disease mechanisms are needed that anticipate clinical disease and are sensitive to functional organism aging. The American Federation for Aging… Continue reading Biomarkers of aging conference in New York City
Similarly to the Edmonton Aging Symposium which reportedly “was a WORLD FIRST! in being streamed live onto the internet” (Kevin Perrott) amongst conferences, a selection of the presentations of the SENS3 conference are now available at the personal website of Richard Schueler. Richard is a big mouthed, cowboy hat geek with a serious life extension… Continue reading SENS3 conference videos online on a personal website
Quick storytelling through citations (alert from Jim Hardy, thanks): Cell: Nutrient-Sensitive Mitochondrial NAD+ Levels Dictate Cell Survival A major cause of cell death caused by genotoxic stress is thought to be due to the depletion of NAD+ from the nucleus and the cytoplasm. Here we show that NAD+ levels in mitochondria remain at physiological levels… Continue reading “Mitochondrial Oasis Effect”: fasting => NAD+ up in mitos => cell survival
Embedded on the slideshow below 9 slides of Michael Rose‘s presentation called Slowing and then stopping aging on the SENS3 conference on the 9th of September. (Photos made by me with the iPhone.) Rose’s argument was: Aubrey de Grey’s original SENS proposal is based on the non-evolutionary assumption that aging is a process of accumulating… Continue reading Michael Rose, evolutionary SENS and aging as a loss of adaptation (slides)
Help me to collect the list of art illustrations that are frequently used and overused by scientists on their slides either as background or as an analogy for some biological or other scientific phenomenon! The first one is the “Fons Juventutis” (“Fountain of Youth“) and now quickly switch to wikipedian composed by Cranach, executed by… Continue reading Hit art illustrations for scientific slides: Fountain of youth by Cranach
Aubrey de Grey‘s presentation in Google Tech Talk series at the Googleplex, Mountain View, May 29, 2007 (Thanks, Russell Whitaker). More on Aubrey on Pimm: Content of Ending Aging, Aubrey de Grey’s coming life extension book 3 Edmonton Aging (Life Extension) Symposium videos Blogterview with Aubrey de Grey: life extension stories
As you might know Technorati, the premiere blog search engine was redesigned about a week ago, and now it is intended to be a more universal search engine which is mirrored in the current subtitle on the page: “Zillions of photos, videos, blogs and more.” Here is what you can find after typing the term… Continue reading Everything Technorati knows about life extension
You can now pre-order Ending Aging: The Rejuvenation Biotechnologies That Could Reverse Human Aging in Our Lifetime at Amazon written by Aubrey de Grey and Michael Rae which is the most detailed, although popular exposition of the SENS (Strategies for Engineered Negligible Senescence) plan to defeat aging. Aubrey was kind enough to mail me the… Continue reading Content of Ending Aging, Aubrey de Grey’s coming life extension book
According to the organizers the Edmonton Aging Symposium “was a WORLD FIRST! in being streamed live onto the internet.” Now you can download where possible, the video, powerpoint and audio MP3 recordings of the streaming split up by speaker in alphabetical order. I think this is really webhistorical and good news for all open access… Continue reading Edmonton Aging Symposium: full video, audio and presentation access
In recent culture, technological life extension is considered to be a form of hacking, as 2Dolphins says a “hacker is someone who enjoys the intellectual challenge of creatively overcoming or circumventing limitations — someone who makes things work beyond perceived limits through unconventional means or skills.” In hacking there is also a DIY element too.… Continue reading Life extension: body hack and/or life hack?
Following Reason’s links at Fight Aging here is a little conference webcasting from the Edmonton Aging Symposium. You also can read a Conference Report at Ouroboros. There was a Symposium Live Streaming where for the very nominal fee of $5 CAD per connection to cover bandwidth costs people could watch the majority of presentations in… Continue reading 3 Edmonton Aging (Life Extension) Symposium videos
Upon a discussion with Anna 1 month ago, the question arised whether life extension might be interpreted as a green idea. She offered, that if people have the opportunity to extend their life significantly, paralell with this situation they find themselves in a more or less environmentalist position. Now back 2 steps: the question of… Continue reading Extension of life in green
The Coalition to Extend Life launched today an online petition to U.S. Congress and President in order to make the technological possibility of Indefinite Life Extension a national priority and public policy goal of the United States. They ask the power people to create the 4 main conditions that will make it possible. 1. a… Continue reading Unlimited Life Extension Petition to U.S. Congress and President: a good address?
The incentive of this argument is a comment on a post over at fellow life extension blog Fight Aging! titled You Can’t Row the Whole Distance With Oars Made of Stem Cells. 1. Currently the biggest grants in life sciences are in regenerative medicine and stem cell biology. 2. The rate of progress is very… Continue reading An argument supporting systemic regenerative medicine as a life extension tool
Check out Grailsearch.org, which was started at the end of January and is hosted by software engineer Jim Craig with a deep interest in aging and bioinformatics. Grailsearch is a “community web portal intended for use by biogerontologists, students of biogerontology, software engineers, biochemists or anyone else interested in working towards the search for systems… Continue reading Grailsearch.org: aging information from a systems biology perspective
Truth to be told I am not really interested in the Resveratrol story neither as a researcher nor as a life extension supporter. First, it is about classical pharmacology, seeking the molecular targets of a relatively simple molecule back and forth, testing its effect on different animals with standard setups, no hint at a new… Continue reading Resveratrol goes to the clinic: a Pulitzer for David Stipp!
Now we are after the Steve Jobs Keynote introducing the iPhone at Macworld Expo in San Francisco. I don’t know if the iPhone line will be the ultimate portable digital device everybody is dreaming about, but I do know, that when partial immortalization as a technology will be first introduced it will be by definition… Continue reading Steve Jobs style partial immortalization keynote: the iPimm
The Edge Annual Question — 2007 for science and technology driven people is: What are you optimistic about? Why? In my opinion it seems rational to be optimistic about things which are in my range or at least I can do something for them. So being a stem cell biologist I am really optimistic about… Continue reading 2007 Edge Optimistic Question: systemic regenerative medicine