Edmonton Aging (Life Extension Technologies) Symposium starts, March 30-31.

The Edmonton Aging Symposium starts today. Based on the program and speakers you can expect hot debates: Huber Warner, Aubrey de Grey, Irina Conboy, Amit Patel, Judith Campisi. I hope that the discussions will be hot, clarifying, perspective and scale conscious (quantitative enough), backed by strict scientific arguments. The organizing principle of the sessions seems… Continue reading Edmonton Aging (Life Extension Technologies) Symposium starts, March 30-31.

Regaining self-renewal: actual and potential stem cells

Have you ever thought that transit-amplifying progenitor cells have the potential to repopulate the damaged stem cell niche through regaining self-renewal capability in vivo? According to András Simon and Jonas Frisén in Cell’s From Stem Cell to Progenitor and Back Again: “It has long been suspected that cells other than those that maintain homeostasis (actual… Continue reading Regaining self-renewal: actual and potential stem cells

Bone marrow cells and ejection fraction improvements in the human heart

The crucial question of every stem cell transplantation whether the cellular incorporation or other happenings (paracrine effects) results in any functional improvement. In heart it was showed that functional and metabolic regeneration of infarcted and chronically avital tissue can be achieved in humans using transplantation of bone-marrow-derived cells {Brehm and Strauer, 2006, Nat Clin Pract… Continue reading Bone marrow cells and ejection fraction improvements in the human heart