Big volume brain repair through escaped neural stem cells in mice

In the 15th, December Cell issue Kuo et al. published a study according to which “mice whose brains were severely damaged by loss of the genes “Numb” and “Numblike” in one region just after birth showed substantial mending within weeks. The researchers attributed that repair to neural stem cell “escapees” that had somehow retained or restored the genes’ activity and, with it, their regenerative potential.” Effectively a big brain hole was largely repaired. The finding casts a light on the amplification of the neural plascticity in the subventricular zone stem cell niche. Here you can read the abstract.