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Archive for June 26th, 2007

Off-the-shelf skin replacements are on their way…

Posted by attilachordash on June 26, 2007

UK scientists in artificial skin breakthrough: “A long-lasting artificial skin has been developed by British researchers. The Cambridge-based Intercytex Group Plc has announced that tests had produced promising results in healing wounds in early clinical trials…. ICX-SKN is created from a matrix produced by the same skin cells that are responsible for synthesising new tissue in the body. Results show that the new skin had produced a closed and healed wound site after just 28 days.”

skinreplacementICX-SKN

Questions: exactly what skin cells and what matrix?
What is the maximal wound area that could be healed with ICX-SKN?

Posted in UK, regenerative medicine, therapy, tissue engineering, treatment | Leave a Comment »

Mr. Gunn’s dissertation on blog: Investigating the role of MSCs in repair of bone

Posted by attilachordash on June 26, 2007

Mr Gunn’s thesis is in a far more advanced stage, and even nerdier than mine.  :)

mrgunn’sthesis

Posted in USA, biology, blogxperiment, bone marrow, open science, open source, regenerative medicine, science, science blogs, stem cells, thesis | 1 Comment »

Choosing a proper title for the thesis: The physiologic role of stem cells…

Posted by attilachordash on June 26, 2007

marie curie’s doctoral thesisIn my last “live” thesis post I said that the first steps of building a thesis are: figuring out a unifying concept behind all my experimental work and finding a proper thesis title.

During my PhD work I’ve done various stem cell transplantations (local and systemic) into brain, heart, muscle tissues using different stem cell sources, just like freshly isolated bone marrow derived cells (hematopoietic, mesenchymal stem cells), murine embryonic stem cells, cultured hematopoietic stem cells. And I was heavily involved in the mechanisms by which exogenous stem cells can contribute to host tissues and the way these exogenous cells and lesion models can motilize the built in endogenuous stem and progenitor cell populations. So for me the unifying concept behind is a kind of systemic approach, that is to collect many stem cell data from various tissues, organs, compare them to each other and derive some unifying principles from them that could be adapted to other tissue environments too. And I really would like to introduce some systemic point of view into stem cell biology and regenerative medicine.

Next is finding a proper title for the thesis which embraces the systemic concept, simple but scientific enough to be approved by the academic people. Also it must be broad enough and not too restricted.

My first, rough idea was: Stem cells‘ regenerative mechanisms in tissues with different regenerative potential (turnover) Read the rest of this entry »

Posted in blogxperiment, open source, open-access, science, science blogs, stem cells, thesis | 2 Comments »