Mark Hamalainen is a young PhD student at Cambridge University at the mitochondrion lab of Ian Holt. Mark received a Bachelor of Science Honours degree in biochemistry and computing from Queen’s University in Kingston, Ontario. He also had research training as a visiting scholar at the California Institute of Technology and the Biodesign Institute at Arizona State University. Mark’s research project is MitoSENS, the artificial transfer of mitochondrial genes to the nucleus in order to defend mitohondrial DNA from the high mutation rate. The technical difficulties of such a project are characterized in this article. The idea generator behind is Aubrey de Grey. I met Mark yesterday at the Eagle Pub and we had a very nice conversation on life extension technologies, strategies and philosophies.
1. What is the story of your life extension commitment? From a very early age (before I can even remember for myself, my family has informed me indirectly), I’ve had a strong fear of death and love of life. Later on, I discovered science fiction and realized that other people had ideas about overcoming death. In high school I began investigating how close science was to implementing life
extension, first in popular non-fiction books, then in scientific journals. This search inevitibly led me to the work of Aubrey de Grey, and shortly thereafter I became involved with SENS research for the Methuselah Foundation.
2. Is it a commitment for moderate or maximum life extension? Maximum. Though I prefer the term ‘indefinite’. Read the rest of this entry »





