Pimm – Partial immortalization

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Archive for November 27th, 2006

New key protein player in mitochondrial fission and fusion: make or break

Posted by attilachordash on November 27, 2006

Regulators of the balance between mitochondrial fusion and fission events are of special interest. November 27, Journal of Cell Science: Katsuyoshi Mihara and colleagues identified a mammalian protein – mitofusin-binding protein (MIB) – that regulates mitochondrial fusion by interacting with mitofusins (Mfns), mitochondrial outer-membrane GTPases that are required for mitochondrial fusion. Overexpressed MIB induces mito fragmentation, silenced MIB by RNAi induces expansion of mitochondrial network fusion structures, inhibits cell growth. Link

Posted in biology, mitochondria, peer-review, science | Leave a Comment »

Questions to contra life extensionists: rational pitfalls

Posted by attilachordash on November 27, 2006

Critical thinking is crucial to every successful scientific and technological project. In order to consider any attempt to the extension of life in details,we have to take a look at the other side of the coin. So in the future I try to blogterview some experts, scholars, philosophers, activists, …who are opposing some concrete points concerning life extension with the questions below:

1. What is the story of your contra life extension commitment?

2. Is it against moderate or maximum life extension?

3. Do you support moderate life extension? If not, what are your arguments against it?

4. What is your (strongest) argument against maximum life extension?

5. What are the problems with moderate life extension technologies concerning humans and why?

6. What are the problems with the present technological drafts of maximum life extension?

7. What can You do against life extension?

Posted in Aubrey de Grey, aging, anti-aging, biotechnology, blog, body hack, idea, life extension, longevity, movement, partial immortalization, philosophy, technology, therapy, treatment | Leave a Comment »