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The Life Scientists
Posted by attilachordash on October 19, 2006
One previous post of Pimm was about the advantages of online, open source-like science protocol videos. So thanks to Sri Kosuri, here is an early sample protocol movie (3 parts) made by John Cumbers on the preparation of fixed chromatin from Drosophila embryos to use the DNA in a genomic array technology, developed in Rob White’s Cambridge lab.
Posted in US, USA, biology, biotechnology, diy, idea, open source, presentation, science, technology | 2 Comments »
Posted by attilachordash on October 19, 2006
Dina Gould Halme and David A. Kessler wrote an article, called FDA Regulation of Stem-Cell–Based Therapies in The New England Journal of Medicine. The key concerns are:
i., Stem-cell–based products as therapeutic agents are or could be: biologic products, drugs, devices, xenotransplantation products, human cells, tissues, and cellular and tissue-based products. Human cells, tissues, and cellular and tissue-based products is defined as “articles containing or consisting of human cells or tissues that are intended for implantation, transplantation, infusion, or transfer into a human recipient.”
ii., Donor’s risk of transmitting infectious or genetic diseases
iii., Contamination or damage risk of the cell or tissue processing: expansion or differentiation of the cells are minimal manipulations, nonhuman fetal calf serum as possible prion source, anymal feeder cells, karyotypic =genetic stability through passages,
iv., Cell types: purity, potency, characterization, the expression pattern of identifying markers
v. In vivo safety and efficacy: experiments in animal models, tumorigenicity
vi., Stem-cell–based products and gene therapy
Image source
Posted in FDA, Mprize, US, USA, biotechnology, embryonic, industry, law, medicine, patent, politics, regenerative medicine, regulation, society, stem cells, therapy, treatment | Leave a Comment »
